Ginkgo biloba exocarp contains high content of phenolic acid compounds, which has anti-tumor, anti-inflammatory, anti-allergic, antibacterial, pest control and other effects. It can be used as an additive for daily chemical products and is an active ingredient worth developing. 80% industrial ethanol is selected as the leaching solvent, and the macroporous adsorption resin is used for enrichment and separation of ginkgolic phenolic acid. The method has the advantages of high selectivity, good separation effect, less solvent loss and relatively low cost.