Changshan contains the active ingredient Huang Changshan alkali, referred to as Changshan base, mainly Huang Changshan alkali a. The antipyretic base and the isothermal base separated from the roots and leaves are correspondingly yellow Changshan base B and yellow Changshan base a. Mainly used in heat-clearing and detoxification, antihypertensive, anti-viral, supplementation of antibodies and so on.The macroporous adsorbent resin is used as an adsorbent, and the Changshan base is adsorbed and purified from the aqueous solution by physical adsorption. The method has the advantages of simple equipment, easy operation and high product purity. Therefore, the macroporous resin adsorption method is increasingly widely used in the purification and purification of Changshan alkali.