Mulberry leaves are the leaves of mulberry trees. Mulberry leaves are sweet, bitter, and cold. Modern pharmacological studies have shown that the total flavonoids contained in mulberry leaves have anti-oxidation, anti-aging, blood sugar lowering, blood lipids, and antibacterial effects. The resin adsorption method can effectively extract the total flavonoids from mulberry leaves, and has the advantages of safety, simplicity, and reusability.