Dipotassium glycyrrhizinate is refined from licorice. Licorice is a perennial herb with a plant height of about 1-1.5m, small dark green leaves, yellow, blue and violet flowers, and sweet roots. Licorice is a traditional Chinese herbal medicine. It has the effects of resolving phlegm, moisturizing skin, anti-inflammatory, anti filtering pathogens, anti hepatotoxin and antibacterial.

Role of dipotassium Glycyrrhizinate in cosmetics:

Dipotassium glycyrrhizinate can penetrate into the skin and maintain high activity, whiten and effectively resist oxidation. It can effectively inhibit the activities of many enzymes in the process of melanin production, especially tyramine enzyme; At the same time, it also has the effects of preventing skin roughness, anti-inflammatory and antibacterial. Dipotassium glycyrrhizinate is a whitening ingredient with good curative effect and comprehensive function. Dipotassium glycyrrhizinate is a whitening cosmetic additive introduced by MARUZEN company in Japan in 1989. After years of use, it has obvious effect and good safety. It is the main functional ingredient of high-grade whitening cosmetics in the world.

Whitening principle of dipotassium glycyrrhizinate:

1. Inhibit the production of reactive oxygen species: dipotassium glycyrrhizinate is a flavonoid compound with strong antioxidant activity. Some researchers used superoxide dismutase SOD as the control group. The results showed that dipotassium glycyrrhizinate could effectively inhibit the production of reactive oxygen species.

2. Inhibition of tyrosinase: compared with common whitening raw materials, the inhibition IC50 of tyrosinase by potassium glycyrrhizate is very low. Dipotassium glycyrrhizinate is recognized as a strong tyrosinase inhibitor, which is better than some commonly used raw materials.

3. Inhibition of melanin production: select the back skin of guinea pigs. Under UVB irradiation, the skin pretreated with 0.5% dipotassium glycyrrhizinate has a higher skin white coefficient (L value) than the control group, and has a significant effect. The experimental results show that dipotassium glycyrrhizinate can significantly inhibit melanin production, which can be used to prevent skin pigmentation and melanin production after sunburn.