Luo hanguo has the effect of relieving cough, resolving phlegm, moistening lungs and lowering blood pressure, and can treat tuberculosis, asthma, acute and chronic bronchitis and other diseases. The curative effect of Luo hanguo is produced by saponins of Luo hanguo. Macroporous adsorption resin is used to extract saponins from Luohanguo, which has the advantages of simple technology, low cost, high yield, and no residual toxicity of metal and organic solvents.