Periwinkle is an important medicinal plant in the vinca flower of the oleander family. So far, more than 70 alkaloids have been isolated, of which vinblastine and vincristine have value, and vincristine acts on tumor cell tubulin. It interferes with the metabolism of tumor cells, and the main clinical tributary of acute lymphoblastic leukemia is also used for breast cancer, bronchial lung cancer, soft tissue sarcoma and the like.