Bilirubin is mainly a metabolite of hemoglobin in aging red blood cells. If the bilirubin is excessively produced or the metabolic pathway is blocked, it will lead to the accumulation of a large amount of bilirubin in the body, which will have a toxic effect on the human body. The overmuch bilirubin must be removed.

The macroporous adsorbent resin has wide adaptability, low cost, and can design the adsorption structure in a targeted manner, and thus is widely used for separation and removal of bilirubin.