Berberine is an important alkaloid that can be extracted from plants such as berberine, cork, and three needles. It has a remarkable bacteriostatic effect. Berberine can fight against pathogenic microorganisms and inhibit various bacteria such as dysentery bacilli, tuberculosis, pneumococcal bacteria, typhoid bacillus and diphtheria bacilli. It is commonly used to treat gastrointestinal diseases such as bacterial gastroenteritis and dysentery. .