Glycyrrhizic acid is not only widely used in medicine, but also used in food, sanitation, light industry and so on. It has the function of preventing sand and sand and improving soil. In recent years, people have been studying the separation and purification of glycyrrhizic acid technology, which has improved the yield and reduced the cost. This research is of great significance for the development of separation and purification technology of glycyrrhizic acid.  The adsorption resin has good exquisite effect on glycyrrhizic acid, and has a large adsorption amount of glycyrrhizic acid, and the elution solution has good separation effect, and the product has good adsorption effect and higher purity.