Vitamin B12, also known as cobalamin, is a generic term for a class of porphyrin-containing compounds. VB12 is an important water-soluble vitamin. It participates in various metabolisms in the form of coenzymes and promotes the synthesis of DNA and proteins. In the absence of VB12, it causes pernicious anemia and damage to the nervous system.

The macroporous adsorbent has good selectivity, easy desorption, stable physical and chemical properties, high mechanical strength, and can be repeatedly used. It has been proved that VB12 is extracted by macroporous adsorption resin, the saturation adsorption amount is high, the elution peak is concentrated, and the amount of eluent is small. The advantages are obvious.