Liquid Preparation & Filling Machine, buy Automatic plastic ampoule bottling blow fill seal machine pharmaceutical Oral liquid filling packing machine on China Suppliers Mobile

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Product Description

Aseptic Blow-Fill-Seal System

BFS is short for Blow-Fill-Seal technique. It has been developed so that formation for the container, filling and sealing takes place in a single machine under a controlled environment that enables the packaging of a pharmaceutical liquid in an aseptic manner. As the container is made, filled and sealed within a single machine and protected by sterile laminar air, the chance of contamination is very remote. Moreover, during the whole cycle, all process media like solution, air & etc. are previously sterile filtered and open containers remain exposed to the clean room air for less than 1.5 seconds. The Blow-Fill-Seal technology become the process of choice when contamination of particle and microbial are primary concerns in a production.

Blow-Fill-Seal Technique

The Blow Fill Seal Technique has been developed so that formation of the container, filling and sealing takes place in a single machine under a controlled environment that enables the packaging of a pharmaceutical liquid in an aseptic manner. The following picture show the major phases in the integrated packaging of parenteral solutions using the AFP® system. Aseptic packaging process As the container is made, filled and sealed within a single machine and the process is protected using a sterile air shower and additionally, all process media (solution, air etc.) are sterile filtered, the
chance of contamination is very remote. Adding to the fact that during the whole cycle, open containers remain exposed to the clean room air for less than 1.5 seconds, the Blow-Fill-Seal technology becomes the process of choice where contamination of particle matter and microbial contamination is a primary concern.

Extrusion

With high speed screw rod, thermoplastic material is continuously extruded in a tubular shape. Aseptic air blows to the plastic tube parison, and the parison goes through the forming mould.

Blowing

The main forming mould closes and the bottom of plastic parison is sealed. The cutting knife cut the parison.The top of plastic parison is located by the open protecting clamp.Aseptic air continuously protects the open tube parison.The plastic material is formed into containers as determined by the design of the mould by vacuum and/or aseptic compressed air

Filling

The containers are filled immediately and the air in the container is displaced .In the filling process,the containers are
protected by the aseptic air as Grade A.

Sealing

At the same time,the tube parison between top of plastic mould and the open protecting clamp remains semi-melting condition,and then the sealed mould closes and forms the top of the container and keeps the container sealed.

Outfeeding

After sealed, the mould is opened, and the containers are totally formed, filled, sealed and is ready to outfeed. Then the machine starts the next cycle.

Detailed Images

Technical Parameters

Model	Specification	No.of Extruding Heads	Distribution of Cavity	Total Cavities	Capacity(pcs/h)
AFPL6	500ml	6	6	6	1150
AFPL6		1000ml	6	6	6	1080
AFPL8	100ml	8	8	8	1950
		250ml	8	8	8	1800
		500ml	8	8	8	1550
AFPL6D	500ml	6	2*6	12	2350
AFPL6D		1000ml	6	2*6	12	2460
AFPL8D	100ml	8	2*8	16	4000
		250ml	8	2*8	16	3600
		500ml	8	2*8	16	3100

Product Application

This product biological preparation hyaluronic acid human and animal vaccine eye drops for injection drug sterile preparation and other fields are applicable

Old style optical, aural, nasal care products need adding preservative in order to assure a controllable shelf life after opening. Whereas no preservatives needed for the dispos-able&quantitative ampoules produced by BFS machine, therefore there is no allergy
risk for patients.

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Company Information

Sino Pharmaceutical Equipment Development (Liaoyang) Co., Ltd. (SINOPED) is a professional manufacturer and supplier of pharmaceutical and chemical machinery and equipment in China. We belong to SINOPEC International Group. We have a well-experienced team to manufacture pharmaceutical machinery and equipments and a professional design institute. With rich experiences in pharmaceutical machinery and equipment field and numbers of professional engineers, we have designed and developed many types of machinery and equipments including clean room project, soft-gel production line, glass-lined reactor, fermentor, centrifuge, granulator, mixer, dryers, pulverizer, tablet press, soft and hard blister packing machine, capsule filling machines, cartoner and rollers, etc. Due to our good credit and service, , we have made great achievements in the past years. We have established long-term business relations with many customers and some of our overseas customers have appointed us to be their purchase agency in China. Our products are exported to many countries & areas, such as Korea, India, Indonesia, Pakistan, Thailand, Vietnam, Japan, Denmark, Romania, Bulgaria, Russia, South Africa, Nigeria, the USA, Australia, Canada, Argentina and Chile. Besides machinery and equipment, we also supply production lines and turn key projects.

In SINOPED you can get your desired goods with the best prices and good quality. Welcome your enquiries from all over the world.

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