Specifications

Giant knot weed extract
Trans-resveratrol 50%, 98%
Low Emodin content
100% pass 80 mesh

 

                                 Giant knot weed extract

 

 

Resveratrol

 

CAS No: 501-36-0

 

Extraction Method: Grain Alcohol

 

Country of Origin: China

 

Active Ingredient: Resveratrol (trans)

 

Form: Fine Brown to white Powder

 

Molecular Weight: 228.24

 

Molecular formula: C₁₄H₁₂O₃

ENGLISH NAME: Resveratrol

Specification: 5%-99%

Content Test: HPLC

Resveratrol

 

Huzhang ("tiger cane") or giant knotweed is an east Asian species (Polygonum cuspidatum), belonging to the Polygonaceae family. Documented uses in traditional Chinese medicine date to the first century BC, and contemporary medical uses supported by clinical results include acute microbial infections or viral hepatitis, chemo- or radiation-induced leukocytopenia, atherosclerosis, and hyperlipidemia.

 

Resveratrol is a naturally occurring phytoalexin produced by some higher plants in response to injury or fungal infection. Phytoalexins are chemical substances produced by plants as a defense against infection by pathogenic microorganisms, such as fungi. Alexin is from the Greek, meaning to ward off or to protect. Resveratrol may also have alexin-like activity for humans. Epidemiological, in vitro and animal studies suggest that a high resveretrol intake is associated with a reduced incidence of cardiovascular disease, and a reduced risk for cancer. 

Quality data

 

 

Identification	Standardization
Aspect	white fine powder
Odor & taste	Characteristic
Particle size	NLT 95% through 80 meshes
Loss on drying	5.0% max.
Sulphated ash	5.0% max.
Heavy metals	20ppm max.
Pb	2ppm
As	2ppm

 

Microbiological data

Total aerobic count	Not more than 1000cfu/gram
Yeast & Mold	Not more than 100cfu/gram
E. Coli	Absence in 10g
Salmonella	Absence in 10g

Addition data

Sterilization	High temperature and press
Storage	Store in a cool dry place, avoiding sunlight directly
Shelf life	Two years when sealed well
Packaging	Food grade multiplayer polyethylene bags, 25kg in one type cardboard drum

 

Function:

1. The analgesic effect and fever

Resveratrol, through a variety of different ways to play therapy efficacy, the display have antipyretic and analgesic activity, as in mice and rats complete institute (Lin and hu, 1987). It extracts show shall be given in case does not affect blood pressure to stomach mucous membrane resistance caused by gastric secretion suppressed ability of stress ulcer.

2. Cancer, mutation resistance

As an antioxidant, anti mutation agent and anti-inflammatory agent, resveratrol shows for cancer chemoprevention ability. It also can induce the body early young myelocytic leukemia cell differentiation (value-added) and inhibition of mouse breast cancer tissue lesions before development. Resveratrol also inhibit protein tyrosine kinase a catalytic tyrosine phosphorylation of substances. The kinase involved in regulation of cell mitosis in the cytoplasm of information transmission. The use of resveratrol inhibits protein tyrosine kinases can by preventing kinase plays a role of resistance mutations and function.

3. Prevent heart and liver damage

Resveratrol inhibits the mice liver triglycerides and cholesterol deposition. It also can inhibit fat mice liver peroxidation and prompted aspartic acid transaminase and propyl amine acid transaminase levels rise. Analysis of these two kinds of enzymes in serum to give a good diagnostic information in the heart and liver damage.

4. The antithrombotic function

Resveratrol inhibits synthesis of lipoxygenase, this enzyme exists in white blood cells, heart, brain, lung and spleen. Thus, resveratrol can prevent the formation of blood clots in blood vessels. And also can inhibit platelet after clonidine the antihypertensive drug treatment of a rally.

5. Promote the immune system activity for wound treatment

Resveratrol also by enhancing the immune system and promote healing of burn. ROM (1993) studied the resveratrol in restoring scald in mice by inhibiting cell sex, humoral and nonspecific immune efficacy. Controlled use of resveratrol provides the immunoregulatory effects of a drug depend on the type. ROM (1995) with different degree such as severe scald in mice studies have shown that resveratrol can restore its ability to function as a response to antigen signal damaged, and proliferation, interleukins Ⅱ synthesis and by lymphocyte antibody synthesis ability. Severe burns after using controlled resveratrol treatment of animals its level of neutrophil and neutrophil adhesion rate return to near normal levels, and prolong survival time.