Latin Name                    Auricularia auricula

Chinese Name                 Hei Mu Er /

Family                        Auriculariaceae

Part of the Plant Used           Fruiting Body

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Active Ingredients              polysaccharides

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Product Specification

25% polysaccharides (UV-VIS)

Brown fine powder

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Product Introduction

Auricularia auricula is commonly known as Judas's ear fungus or Jew's Ear. It has been used for centuries in China, particularly to cure hemorrhoids and strengthen the body. Sometimes it is also used to treat hemoptysis, angina, diarrhea, and ward against gastrointestinal upset.

Physiological Functions

Auricularia auricula Extract is very famous because of its anticoagulant activity:

An acidic polysaccharide with anticoagulant activity was isolated from the edible mushroom Auricularia auricula using water, alkali or acid extracts. The alkali extract showed the highest anticoagulant activity and was thereby further purified using gel filtration chromatography. Specific anticoagulant activity of the purified polysaccharide was 2 IU/mg and its average mass was approximately 160 kDa. The polysaccharide from Auricularia auricula contains mainly mannose, glucose, glucuronic acid and xylose but no sulfate esters. Its anticoagulant activity was due to catalysis of thrombin inhibition by antithrombin but not by heparin cofactor II. Inhibition of Factor Xa by antithrombin was not catalyzed by the polysaccharide. The glucuronic acid residues were essential for the anticoagulant action of the mushroom polysaccharide since the activity disappeared

after reduction of its carboxyl groups. In ex vivo tests using rats orally fed with the polysaccharide, we observed an inhibitory effect on platelet aggregation as observed with aspirin, a well-known antiplatelet agent. The polysaccharides from these mushrooms may constitute a new source of compounds with action on coagulation, platelet aggregation and, perhaps, on thrombosis.

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Applications

Pharmaceutical stuff

Functional food and food additive