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DESCRIPTION

General description

Retention Mechanism: Reversed-phase

Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)

l Hydrophilic modified styrene polymer

l Developed for the extraction of a highly broad range of compounds from aqueous samples

l Retention predominately based on reversed-phase; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.

l Examples of more polar compounds that are retained and recovered include (but not limited to): pyridoxine (logPo/w -0.56), riboflavin (logPo/w -2.02), biotin (logPo/w 0.11).

Application

HLB SPE Tube may be used as an extraction cartridge for the solid phase extraction and analysis of pharmaceuticals and personal care products in water samples using high performance liquid chromatography combined with tandem mass spectrometry.

Features and Benefits

l Excellent sample prep performance at a lower price

l Amenable to generic methodology - save time, money, and headache during method development

l Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing

l Resistance to overdrying allows for more robust methdology

l Low UV and MS extractables for lower background and greater sensitivity

l Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision

     HLB 6cc/200mg     HLB 6cc/500mg

     HLB 3cc/60mg       HLB 3cc/200mg etc.