3. Supercritical CO2 Extraction

4. Small order available

5. OEM capsule available
6. Sample free available

7. Shelf life:3 years

8. GMP, Kosher,HACCP, ISO certification

Magnolol Bark Extract  , Magnolol 90%

Certificate Of Analysis

Relieve Stress with Honokiol and Magnolol from Magnolia Extract!

     Feeling stressed lately? Take charge of your stress with Magnolia Extract!  How does it work?

     Magnolia extract is rich in the phytochemicals honokiol and magnolol, which have numerous health benefits. One of the most impressive benefits is their ability to alleviate stress while producing a calming effect. Dozens of animal studies have shown that they act as a non-addictive, non-sedating anxiolytic (anti-anxiety and anti-stress) agent at low doses.

     That means a small dose of Magnolia extract can help calm your nerves and alleviate anxiety, without making you sleepy. The beauty about these two phytochemicals is that honokiol exerts an anti-anxiety effect, and magnolol exerts an antidepressant effect.

     When you take Magnolia extract, you're really "killing two birds with one stone"—anxiety and depression—in order to feel better mentally and emotionally.

Honokiol relieves stress without side effects

     Honokiol has a long history of use in traditional Chinese formulas that relieve anxiety without leaving you feeling like you've been drugged. In a recent study to determine whether honokiol depresses the central nervous system in the same way as diazepam (commonly known as Valium®), two groups of mice were treated with honokiol and diazepam before running through a maze. The honokiol group was more relaxed, and finished without any change in motor activity or muscle tone. On the other hand, the diazepam group exhibited several side effects, including sleepiness, disrupted learning and memory, muscle relaxation, and withdrawal symptoms. The results suggest that honokiol is less likely than diazepam to induce physical dependence, central nervous system depression, and amnesia when given at doses that produce an anti-anxiety effect.

     A similar test found that honokiol significantly prolonged the time the animals spent in a maze, suggesting an anti-anxiety effect. Normally, when rodents are placed in a maze, they like to hide rather than explore because they get anxious. These rodents appeared to be more relaxed, and expressed curiosity about their environment. When the animals were given honokiol in various doses over a period of seven days, the effects remained the same: there was no change in motor activity or in the animals' performance. The animals receiving the diazepam (Valium), however, became dependent on the same dose, which hindered their performance.

     Although no studies have specifically been done to show that Magnolia extract reduces cortisol levels, it stands to reason that since so much impressive research has shown that it relieves stress, anxiety and depression, that Magnolia must also reduce cortisol—a by-product of stress.

   We think that more research is needed on the benefits of Magnolia and, in particular, we think research should be done to look at how Magnolia affects cortisol levels.

So far, what we do know is that when compared to pharmaceutical drugs such as Valium (diazepam), honokiol appears to be just as effective in its anti-anxiety activity, but without the strong sedative effect. This makes it an amazingly safe and effective remedy to help relieve the damaging effects of stress, without the tranquilizing side effects of drugs.

Brain health benefits

Other studies have shown that magnolol and honokiol help support normal brain function and protect the brain from Alzheimer's disease by:

• Modulating the activity of various neurotransmitters and related enzymes in the brain
• Increasing choline acetyltransferase activity
• Inhibiting acetylcholinesterase
• Increasing acetylcholine release

Magnolia Extract also promoted and enhanced the survival and growth of injured brain cells.

A small dose of Magnolia extract can help calm your nerves and alleviate anxiety, without making you sleepy.

How safe is Magnolia?

No significant toxicity or adverse effects have been reported to date when it is taken as directed. Amazingly small doses (30 mg) of magnolol and honokiol are effective for anxiety and depression. Large doses exceeding 100 mg may cause a sedative effect and can interact with alcohol, increasing its effects, therefore, driving or operating dangerous equipment should be avoided when taking larger doses of Magnolia extract.

Why take Magnolia extract?

If you, or someone you care about, tend to suffer from stress, anxiety, or depression, Magnolia extract may be just the thing you need to "take the edge off" and improve your quality of life … without the risk of side effects. If you're looking for a potent, natural and safe antidepressant, antioxidant, or anticancer agent, consider adding Magnolia extract to your health regimen. Plant a tree, stop and smell the flowers … and gain a new appreciation for the Magnolia tree.