Specifications
HesperidinCAS NO:520-26-4
Product name: Hesperidin
Resource: Fruit of Citrus aurantium L or Citrus sinensis Osbeck
Formula: C28H34O15
CAS NO.: 520-26-3
Testing Method: HPLC
Quality data
Identification | Standardization |
Aspect | Brown yellow fine powder |
Odor & taste | Characteristic |
Particle size | NLT 95% through 80 meshes |
Loss on drying | 5.0% max. |
Sulphated ash | 5.0% max. |
Heavy metals | 20ppm max. |
Pb | 2ppm |
As | 2ppm |
Microbiological data
Total aerobic count | Not more than 1000cfu/gram |
Yeast & Mold | Not more than 100cfu/gram |
E. Coli | Absence in 10g |
Salmonella | Absence in 10g |
Addition data
Sterilization | High temperature and press |
Storage | Store in a cool dry place, avoiding sunlight directly |
Shelf life | Two years when sealed well |
Packaging | Food grade multiplayer polyethylene bags, 25kg in one type cardboard drum |
Hesperidin is a flavanone glycoside found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin is believed to play a role in plant defense. It acts as an antioxidant according to in vitro studies. In human nutrition it contributes to the integrity of the blood vessels.
Various preliminary studies reveal novel pharmaceutical properties. Hesperidin reduced cholesterol and blood pressure in rats. In a mouse study large doses of the glucoside hesperidin decreased bone density loss. Another animal study showed protective effects against sepsis. Hesperidin has anti-inflammatory effects. Hesperidin is also a sedative, possibly acting through adenosine receptors.
Some in vitro results applied only to the aglucone form. Hesperidin also showed the ability to penetrate the blood brain barrier in an in vitro model.
Hesperidin, in combination with a flavone glycoside called diosmin, is used in Europe for the treatment of venous insufficiency and hemorrhoids. Hesperidin, rutin and other flavonoids thought to reduce capillary permeability and to have anti-inflammatory action were collectively known as vitamin P.
