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Specifications

Betamethasone Cream

COMPOSITION
Betamethasone cream contains 0.1 % Betamethasone as the valerate ester. this Betamethasone cream is a smooth, white, water-miscible preparation.

INDICATIONS
Betamethasone valerate is an active topical corticosteroid which produces a rapid response in those inflammatory dermatomes that are normally responsive to topical corticosteriod therapy, and is often effective in the less responsive conditions such as psoriasis. Betamethasone cream is indicated for the treatment of the following conditions; eczema including atopic, infantile, discoid and staiss eczemas; prurigo; psoriasis (exclusing widespread plaque psoriasis), neurodermatoses, including lichen simplex; lichen planus; seborrhoeic dermatitis; intertrigo; contact sensitivity reactions, discoid lupus erythematosus; generalized erythroderma.

DOSAGE AND ADMINISTRATION
A small quantity should be applied to the affected area two or three times daily until improvement occurs. It may then be pssible to maintain improvement by
applying once a day or even less often.

CONTRA-INDICATIONS
Dermatoses in children under one year of age, including dermatitis and napkin eruptions. Rosacca, acne and peri-oral dermatitis, skin lesions caused by infection with viruses (e.g. herpes simplex chickenpox), fungi (e.g. candidiasis, tinea) or bacteria (e.g. impetigo). Hypersensitivity to the preparation.

PRECAUTIONS
Topical steroids may be harzardous in psoriasis for a number of reasons, including rebound relapses, development of tolerance, risk of generalize pustular psoriasis and development of local or systemic toxicity due to impaired barrier function of the skin. Long term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur even without occlusion. The face, more than other areas of the body may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. This must be borne in mind when treating such conditions as psoriasis, discoid lupus erythematosus and severe eczema with Betamethasone. If applied to the eyelids, care is need to ensure that the preparation does not enter the eye, as glaucoma might result.

SIDE EFFECTS
Prolonged and intensive treatment with highly active corticosteriod preparations may cause local atrophic changes in the skin such as striea, thinning and dilatation of the superficial blood vessels, particularly when occulusive dressings are used or when skin folds are involved. As with other tropical corticosteroids, prolonged use of large amounts, or treatment of extensive areas, can result in sufficient systemic absorption to produce the features of hypercorticism. This effect is more likely to occur in infants and children, and if occlusive dressings are used. In infants, the napkin may act as an occlusive dressing. Betamethasone cream is usually well tolerated, but f signs of hypersensitivity appear, application should stop immediately.

PRESENTATION
In tubes of 20g.