Chondroitin Sulfate
Resource: Bovine cartilage
Reference Standard: USP32/BP/EP
CAS No.: 9007-28-7
Molecular formula: (C14H21NO14S)n
Product Specification: 90.0% to 105.0%
Appearance: White to Off-White Powder
Product Introduction
Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). Since the molecule of chondroitin sulfate has multiple negative charges at physiological pH, a cation is present in salts of chondroitin sulfate. Commercial preparations of chondroitin sulfate typically are the sodium salt. The chondroitin sulfate of Sunfull Company is mostly extracted from bovine cartilage. And it also can be extracted from chicken, porcine and shark cartilage in China. Chondroitin sulfate is an important structural component of cartilage and provides much of its resistance to compression. Along with glucosamine and/or Methyl Sulfonyl Methane(MSM), chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis. Chondroitin is considered safe for human; it is regulated in the U.S. as a dietary supplement by the Food and Drug Administration. In Europe, chondroitin sulfate formulations are approved as drugs with evidenced efficacy and safety demonstrated by clinical trials in osteoarthritis patients. .
Certification of USP33
Items |
Specification |
Appearance | White to off-white Powder |
Clarity and Color Solution | 0.35Max at 420nm |
Specific Rotation | -20.0° — -30.0° |
Assay (CPC) | 95% Min ( O.D.B) |
Loss on drying | ≤10.0% |
PH Value | 5.5-7.5 |
Particle Size | 100%through 100mesh |
Bulk Density | 0.6 |
Content of Protein | 1.5% Max (Dried Basis) |
Residue on ignition | 15%—25% |
Heavy metals(Pb) | ≤10ppm |
Chloride | ≤0.5% |
Total plate count | ≤1000cfu/g |
Yeast & Mold | ≤100cfu/g |
E.Coli | Negative |
Salmonella | Negative |
Clostridium | Negative |
Fuction:
Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).
Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.
As part of aggrecan, chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis.
Advantages:
(1) 25 year experience in pharmaceutical and botanical industry
(2) ISO9001:2008 certificated company
(3) stable business relations with most of the GMP sources in China
(4) Fischer Chemicals AG China office
Packing & Storage
Packing:25kg/drum, inner by plastic bag or aluminium foil bag
Net Weight:25kg/Drum
Gross Weight:28kg/Drum
Size&Volume:510cm*350cm, 0.08m ³/Drum
Storage: Stored in cool and dry places,keep away for strong light
Shelf life:2 Years
Certificate of our company