Tube filling and sealing machine is suitable for filling all kinds of pasty and viscous fluid and the materials alike, into plastic and composite metal tube and then internally heating tubes, sealing and printing lot number. It is used in the industries of pharmaceutics, foodstuffs, cosmestic and daily chemicals. With Taiwan's EVIEW touch screen and Taida's PLC control system employed, convenience, visualized and realiable non-touch operation of the machine is effected compact design and auto tube feed.